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Medchemexpress LLC XE991 dihydrochloride | 122955-13-9 | 99.6% | 449.37 | 10 MG

Supplier: Medchemexpress LLC HY108577100MG
XE991 dihydrochloride is a Kv7 (KCNQ) channels blocker. It potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively. This compound is designed for research applications.
- Potent Kv7 (KCNQ) channels blocker
- Inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current
- Enhances [3H]ACh release from rat brain slices with an EC50 of 490 nM
- Demonstrates good in vivo potency and duration of action
- For research use only
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