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Medchemexpress LLC XL-784 | 1224964-36-6 | 98.25% | 548.92 | 50 MG
SDP

Catalog No. 5000401870
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XL-784 is a selective matrix metalloproteinases (MMP) inhibitor. It is a highly potent, low-molecular-weight inhibitor with limited aqueous solubility. This compound potently inhibits MMP-2, MMP-13, and ADAM10 (TNF-α-converting enzyme (TACE)) activity, with IC50 values typically in the 1-2 nM range. It also demonstrates inhibitory effects on MMP-9 and ADAM17, while exhibiting lower potency for MMP-1. Animal studies have shown that treatment with XL-784 effectively inhibits aortic dilatation.

  • Selective matrix metalloproteinases (MMP) inhibitor.
  • Potently inhibits MMP-2, MMP-13, and ADAM10 activity.
  • Inhibitory effects on MMP-9 and ADAM17.
  • Low-molecular-weight compound.
  • Limited aqueous solubility.
  • Effective in inhibiting aortic dilatation in animal models.
  • Available in various solid forms and as a DMSO solution.

Catalog No. 50-004-01870 Supplier Medchemexpress LLC Supplier No. HY1948550MG
May include imposed supplier surcharges.
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XL-784 is a selective matrix metalloproteinases (MMP) inhibitor. It is a highly potent, low-molecular-weight inhibitor with limited aqueous solubility. This compound potently inhibits MMP-2, MMP-13, and ADAM10 (TNF-α-converting enzyme (TACE)) activity, with IC50 values typically in the 1-2 nM range. It also demonstrates inhibitory effects on MMP-9 and ADAM17, while exhibiting lower potency for MMP-1. Animal studies have shown that treatment with XL-784 effectively inhibits aortic dilatation.

  • Selective matrix metalloproteinases (MMP) inhibitor.
  • Potently inhibits MMP-2, MMP-13, and ADAM10 activity.
  • Inhibitory effects on MMP-9 and ADAM17.
  • Low-molecular-weight compound.
  • Limited aqueous solubility.
  • Effective in inhibiting aortic dilatation in animal models.
  • Available in various solid forms and as a DMSO solution.

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