Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC XL-784 | 1224964-36-6 | 98.25% | 548.92 | 50 MG
Supplier: Medchemexpress LLC HY1948550MG
XL-784 is a selective matrix metalloproteinases (MMP) inhibitor. It is a highly potent, low-molecular-weight inhibitor with limited aqueous solubility. This compound potently inhibits MMP-2, MMP-13, and ADAM10 (TNF-α-converting enzyme (TACE)) activity, with IC50 values typically in the 1-2 nM range. It also demonstrates inhibitory effects on MMP-9 and ADAM17, while exhibiting lower potency for MMP-1. Animal studies have shown that treatment with XL-784 effectively inhibits aortic dilatation.
- Selective matrix metalloproteinases (MMP) inhibitor.
- Potently inhibits MMP-2, MMP-13, and ADAM10 activity.
- Inhibitory effects on MMP-9 and ADAM17.
- Low-molecular-weight compound.
- Limited aqueous solubility.
- Effective in inhibiting aortic dilatation in animal models.
- Available in various solid forms and as a DMSO solution.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?