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Medchemexpress LLC Xmu-mp-3 | 2031152-08-4 | 95.7% | C27H27F3N8O | 10MG
Supplier: Medchemexpress LLC HY13653110MG
XMU-MP-3 is a potent, non-covalent inhibitor of Bruton's tyrosine kinase (BTK) that inhibits both wild-type BTK and the C481S mutant. It demonstrates low-nanomolar biochemical potency and cellular activity, including induction of apoptosis, and is suitable for biochemical and cellular studies of BTK signaling and inhibitor profiling.
- Low-nanomolar biochemical potency (IC50 10.7 nM for BTK WT, 17.0 nM for BTK C481S in the presence of 10 μM ATP).
- Demonstrated cellular activity (BTK-transformed Ba/F3 proliferation IC50 11.4 nM).
- Induces apoptosis in BTK-dependent cell models.
- High chemical purity (95.7%).
- Defined storage stability for powder and solutions.
- Suitable for biochemical assays and cellular mechanistic studies.
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