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Medchemexpress LLC XMU-MP-3 | 2031152-08-4 | 95.8% | 536.55 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY13653150MG

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XMU-MP-3 is a potent non-covalent BTK inhibitor with IC50s of 10.7 nM for BTK WT and 17.0 nM for BTK C481S mutation in the presence of 10 μM ATP. It also induces apoptosis and inhibits the auto- and trans-phosphorylation of BTK at Y223 and Y551.

  • Potent non-covalent BTK inhibitor
  • Induces apoptosis
  • Inhibits BTK-transformed Ba/F3 cell proliferation
  • Maintains inhibitory potency against BTK(C481S)-Ba/F3 cells
  • Substantially suppresses tumor growth in mouse xenograft models

Catalog No. 50-003-51338


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