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Cayman Chemical XnthIn amIn congenr 25mg

Supplier: Cayman Chemical 2307725 MG
A non-selective adenosine receptor antagonist (Kbs = 83, 25, and 15 nM for rat PC 12 cells, human platelets, and rat fat cells, respectively); reduces NECA-stimulated adenylate cyclase activity in human platelets (EC50s = 1 and 0.31 μM in the presence and absence of XAC, respectively); reverses R-PIA-induced inhibition of isoproterenol-stimulated adenylate cyclase activity in rat fat cell membranes (IC50s = 146 and 26 nM in the presence and absence of XAC, respectively); reverses 2-CADO-, R-PIA-, and NECA-induced reductions in heart rate and blood pressure in rats (0.1-1.0 mg/kg); induces convulsions in mice (39.8 mg/kg)
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