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Medchemexpress LLC XP-524 | 2344825-52-9 | 98.0% | 552.65 | 50 MG
Supplier: Medchemexpress LLC HY14700850MG
XP-524 is a potent BET and EP300 inhibitor that has shown significant tumoricidal activity in vivo, preventing KRAS-induced neoplastic transformation and prolonging survival in aggressive pancreatic ductal adenocarcinoma (PDAC) models. It also enhances self-peptide presentation and tumor recruitment of cytotoxic T lymphocytes, making it a promising candidate for PDAC research.
- Potent BET and EP300 inhibitor
- Exhibits tumoricidal activity in vivo
- Prevents KRAS-induced neoplastic transformation
- Prolongs survival in pancreatic ductal adenocarcinoma models
- Enhances presentation of self-peptide
- Improves tumor recruitment of cytotoxic T lymphocytes
- Suitable for research into pancreatic ductal adenocarcinoma
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