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Medchemexpress LLC XPC-6444 | 2230144-21-3 | 98.9% | 100 MG
SDP

Supplier:  Medchemexpress LLC HY128772100MG

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XPC-6444 is a highly potent, isoform-selective, and central nervous system (CNS)-penetrant NaV1.6 inhibitor (IC50 = 41 nM for human NaV1.6). It also effectively blocks NaV1.2 (IC50 = 125 nM) and exhibits anticonvulsant activity.

  • Exhibits anticonvulsant activity.
  • Demonstrates high selectivity over NaV1.1 and NaV1.5 in vitro.
  • Shows good metabolic stability in human liver microsomes and hepatocytes.
  • Low potential for MDR1 mediated efflux.

Catalog No. 50-003-42049


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