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XRP44X, Tocris Bioscience™

Catalog No. 310150
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Catalog No. Quantity
31-015-0 50 mg
31-011-0 10 mg
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Catalog No. 31-015-0 Supplier R&D Systems Supplier No. 3101/50
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Description

Ras-Net pathway inhibitor

Ras-Net (Elk-3) pathway inhibitor (IC50 = 10 - 20 nM). Indirectly inhibits Net phosphorylation upstream of Erk1/2 activation. Mediates G2-M cell cycle arrest, suppresses growth of multiple cell types (IC50 ∽ 2 nM), inhibits angiogenesis and acts as a microtubule depolymerizing agent in vitro.

Chemical Identifiers

CAS 729605-21-4
Molecular Formula C21H21ClN4O
Molecular Weight (g/mol) 380.876
InChI Key NPHPNBGYPKBDDB-UHFFFAOYSA-N
Synonym xrp44x, 4-3-chlorophenyl piperazin-1-yl 3-methyl-1-phenyl-1h-pyrazol-5-yl methanone, 1-3-chlorophenyl-4-3-methyl-1-phenyl-1h-pyrazol-5-yl carbonyl piperazine, 4-3-chlorophenyl-1-piperazinyl 3-methyl-1-phenyl-1h-pyrazol-5-yl-methanone, 1-3-chlorophenyl-4-5-methyl-2-phenylpyrazole-3-carbonyl piperazine, acmc-20ejss, xrp44x hplc, 4-3-chlorophenyl piperazin-1-yl 5-methyl-2-phenyl-2h-pyrazol-3-yl-methanone, 4-3-chlorophenyl piperazin-1-yl 5-methyl-2-phenyl-2h-pyrazol-3-yl methanone
PubChem CID 10339779
IUPAC Name [4-(3-chlorophenyl)piperazin-1-yl]-(5-methyl-2-phenylpyrazol-3-yl)methanone
SMILES CC1=NN(C(=C1)C(=O)N2CCN(CC2)C3=CC(=CC=C3)Cl)C4=CC=CC=C4

Specifications

Quantity 50 mg
Formula Weight 380.87
Percent Purity >99%
Chemical Name or Material Ras GTPase Inhibitors

Safety and Handling

Recommended Storage Store at Room Temperature
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