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Medchemexpress LLC XY-06-007 | 2757045-94-4 | 98.9% | C41H41ClN8O8 | 1 MG
Supplier: Medchemexpress LLC HY1452261MG
XY-06-007 is a selective and potent bump-and-hole (B&H)-PROTAC BRD4BD1L94V degrader that shows strong degradation activity against its target at nanomolar concentrations without affecting off-targets. It exhibits suitable pharmacokinetic properties for in vivo studies, making it a valuable tool for research applications.
- Exhibits a half-degradation concentration (DC50, 6 h) of 10 nM against BRD4BD1L94V.
- Demonstrates suitable pharmacokinetics for in vivo studies.
- Has good plasma concentration, area under the curve (AUC), and bioavailability.
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