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Apexbio Technology LLC Y-27632 dihydrochloride, 146986-50-7, MFCD03490488, 10 mg
SDP

Supplier:  Apexbio Technology LLC A300810

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MF: C14H21N3O2HCl, MW: 320.26, Solubility: 52.9mg/ml in H2O; 16.013mg/mL in DMSO. Y-27632 dihydrochloride is a small-molecule inhibitor of Rho-associated protein kinase p160ROCK with the IC50 of 140 nM. Y-27632 suppresses the kinase activity of both ROCK-1 and ROCK-2 in vitro, and this compound inhibits the kinases by binding to the catalytic site of ROCK-1 and ROCK-2. Thus Y-27632 function on Rho-mediated stress fiber formation, the G1-S phase progression and cytokinesis.

Catalog No. 50-101-2280


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