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Medchemexpress LLC Y-27632 dihydrochloride | 129830-38-2 | 99.9% | 320.26 g/mol | C14H23Cl2N3O | 10 MG
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Supplier:  Medchemexpress LLC HY10583G10MG

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Y-27632 dihydrochloride is an ATP-competitive inhibitor of Rho-associated kinases (ROCK1 and ROCK2) used in research to modulate Rho/ROCK signaling, cytoskeletal dynamics, and cell migration. It is cell permeable, has reported oral activity in models, and has demonstrated antiepileptic effects in studies.

  • ATP-competitive inhibition of ROCK1 and ROCK2 (reported Ki ≈ 220-300 nM).
  • Cell-permeable small molecule for in vitro and in vivo studies.
  • High reported chemical purity suitable for research use.
  • Available in milligram to gram pack sizes and as DMSO solutions for assay preparation.
  • Useful for studies of cytoskeletal regulation, cell migration, and related signaling pathways.
  • Includes CAS and molecular formula identifiers for traceability.

Catalog No. 50-002-42928


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