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Medchemexpress LLC Y-27632 dihydrochloride | 129830-38-2 | MFCD03490488 | 99.9% | 320.26 g/mol | C14H23Cl2N3O | 25 MG
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Supplier:  Medchemexpress LLC HY1058325MG

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Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of Rho-associated kinases (ROCK) used in research to alter cytoskeletal dynamics, cell survival, and differentiation. It selectively inhibits ROCK-I and ROCK-II and has reported antiepileptic effects and applications in stem cell and neurobiology studies.

  • ATP-competitive ROCK inhibitor with Ki values for ROCK-I (220 nM) and ROCK-II (300 nM).
  • Orally active compound applicable in both in vitro and in vivo research.
  • Reported antiepileptic effects in preclinical studies.
  • Modulates apoptosis and promotes mesendodermal differentiation in stem cell models.
  • White to off-white solid with molecular weight 320.26 g/mol and formula C14H23Cl2N3O.
  • High purity suitable for analytical and experimental use.

Catalog No. 50-002-44462


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