Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000347724

Medchemexpress LLC Y-33075 dihydrochloride | 173897-44-4 | 98.81% | 353.25 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY10069

Encompass_Preferred

Y-33075 dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM.

  • Selective ROCK inhibitor with an IC50 of 3.6 nM.
  • Inhibits PKC (IC50 of 420 nM) and CaMKII (IC50 of 810 nM) more potently than Y-27632.
  • Extends neurites in retinal ganglion cells (RGCs).
  • Inhibits the contraction of rabbit ciliary artery segments evoked by histamine in Ca2+-free solutions.
  • Significantly lowers intraocular pressure (IOP) in rabbits and monkeys after topical administration.
  • Increases regenerating axons of retinal ganglion cells (RGCs) in rats.

Catalog No. 50-003-47724


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.