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Medchemexpress LLC YB-0158 | 1144043-83-3 | 99.8% | 703.59 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY13654110MM/1ML

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YB-0158 is a reverse-turn peptidomimetic and a potent targeting agent for colorectal cancer stem cells. It works by disrupting Sam68-Src interactions and inducing apoptosis in colorectal cancer cells, demonstrating anti-cancer activities.

  • Significantly increases apoptosis in colorectal cancer cells, as shown by activated Caspase-3/7 detection assays.
  • Decreases CBP recruitment at the promoter of Wnt/beta-Catenin target genes LGR5 and MYC in HT29 cells.
  • Displays an EC50 (1.64 μM) in cultured MC38 cells.

Catalog No. 50-003-48317


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