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Cayman Chemical YIL 781hydrochlorIde 10mg
Supplier: Cayman Chemical 2921710 MG
An antagonist of GHS-R1a (Ki = 0.017 µM); selective for GHS-R1a over the motilin receptor (Ki = 6 µM) and a panel of 30 receptors and enzymes (Kis = >10 µM); prevents ghrelin-induced decreases in insulin secretion in glucose-stimulated isolated rat pancreatic islets at 1 µM; increases plasma insulin levels and decreases blood glucose levels in rats in an intraperitoneal glucose tolerance test at 0.3 or 10 mg/kg, respectively; inhibits cocaine-induced hyperlocomotion in mice at 10 and 20 mg/kg
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