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Medchemexpress LLC YK-2168 | 2571068-74-9 | 98.1% | 315.80 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1629195MG

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YK-2168 is a potent and selective CDK9 inhibitor with an IC50 of 5.9 nM. It inhibits phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain. YK-2168 induces apoptosis in tumor cells, suppresses expression of CDK9-regulated genes such as MYC and Mcl1, and inhibits tumor growth in CDX mice models. It can be used for the research of cancer, such as leukemia.

  • Potent and selective CDK9 inhibitor
  • Induces apoptosis in tumor cells
  • Suppresses expression of CDK9-regulated genes
  • Inhibits tumor growth in CDX mice models
  • Suitable for research in cancer, such as leukemia

Catalog No. 50-003-92362


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