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Medchemexpress LLC 1-cyclobutyl-3-(2,6-dimethylphenyl)-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2(1H)-one (methoxy-piperazinyl substituted) | 2172617-15-9 | 99.8% | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1200565MG

Encompass_Preferred

YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor for research use. It inhibits SIK1, SIK2, and SIK3 with IC50 values of 6.56 nM, 1.77 nM, and 20.5 nM, respectively. The compound is supplied as a high-purity solid with good DMSO solubility for biochemical and cellular studies.

  • Potent inhibition of SIK1, SIK2, and SIK3 at low-nanomolar concentrations.
  • High purity suitable for research applications.
  • Soluble in DMSO at 16.67 mg/mL (31.59 mM).
  • Solid storage recommended at -20°C; in solution store at -80°C for long-term stability.
  • Available in small research sizes for assay development.

Catalog No. 50-193-2546


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