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Invitrogen™ Human YKL-40 ELISA Kit

Catalog No. BMS2322
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96 Tests
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BMS2322 96 Tests
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ELISA

The Human YKL-40 (CHI3L1) ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative detection of human YKL-40.

Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number 39 kDa synovial protein; ASRT7; AW208766; Breast regression protein 39; Brp39; BRP39 protein; Cartilage glycoprotein 39; CGP39; CGP-39; Chi3l1; Chil1; chitinase 3 like 1; Chitinase 3 like protein 1 CGP 39; chitinase 3-like 1; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase 3-like 1 protein; chitinase-3-like protein 1; chitinase-like 1; DKFZp686N19119; FLJ38139; Gp39; GP-39; hCGP39; HC-gp39; hCGP-39; HCGP-3 P; YKL40; YKL-40; YYL-40
Assay Range 78 to 5000 pg/mL
Assay Sensitivity 10.83 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Cell Lysates, Plasma, Serum
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 1116
Gene Symbol CHI3L1
Interassay CV 7.2%
Intraassay CV 2.3
Kit Contents Pre-coated 96 well plate, Standard (2 vials), Assay Buffer concentrate, Biotinylated Detection Antibody, Streptavidin-HRP, Wash Buffer, Substrate Solution, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Cell Lysate 5 μL, Plasma 5 μL, Serum 5 μL
Storage Requirements 2°C to 8°C
Target CHI3L1
Test Time 1 hrs 20 mins
Total Assay Time 3 hrs 30 mins
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