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Medchemexpress LLC HY-101257B 5mg Medchemexpress, YKL-5-124 (TFA) CAS:0 Purity:>98%
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Supplier:  Medchemexpress LLC HY101257B5MG

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Medchemexpress, HY-101257B 5mg YKL-5-124 (TFA) CAS:0 YKL-5-124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively. YKL-5-124 TFA is >100-fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL-5-124 TFA induces a strong cell-cycle arrest, inhibits E2F-driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Catalog No. 50-202-9487


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