Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC YL-5092 | 3056857-07-6 | 99.8% | 441.43 | 1 ML
Supplier: Medchemexpress LLC HY16460710MM/1ML
YL-5092 is a selective YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) inhibitor with an IC50 of 7.4 nM and a KD of 29.6 nM. It can suppress cancer cell proliferation and induce cell G0/G1 phase arrest and apoptosis. YL-5092 is used for cancer research, including acute myeloid leukemia (AML).
- Selectively inhibits YT521-B homology (YTH) domain-containing protein 1.
- Suppresses cancer cell proliferation.
- Induces cell G0/G1 phase arrest.
- Promotes apoptosis in cancer cells.
- Impairs leukemogenesis and improves survival rates in mouse tumor models.
- Reduces leukemia infiltration in peripheral blood, spleen, and bone marrow.
- Decreases the expression of YTHDC1 target genes like MYC, FOXM1, GINS1, MCM2, MCM4, and MCM5.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?