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Medchemexpress LLC Yl-5092 | 3056857-07-6 | 99.8% | 441.43 | C22H14F3N3O2S | 10 MG
SDP

Supplier:  Medchemexpress LLC HY16460710MG

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YL-5092 is a selective inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) with potent biochemical activity and demonstrated efficacy in acute myeloid leukemia models. It is used in research probing m6A-mediated RNA regulation and cancer biology, and is supplied as a characterized, high-purity solid for in vitro and in vivo studies.

  • Selective inhibition of YTHDC1 (IC50 7.4 nM; KD 29.6 nM).
  • Demonstrated cellular activity against AML cell lines and efficacy in xenograft models.
  • Induces G0/G1 phase arrest and apoptosis in cancer cells.
  • High reported purity and defined physicochemical properties for reproducible results.
  • Soluble in DMSO (100 mg/mL) and formulatable for in vivo use (≥2.5 mg/mL in standard vehicle).

Catalog No. 50-002-89291


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