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Medchemexpress LLC YL-939 | 3023925-68-7 | C25H26N6O | 100 MG
SDP

Supplier:  Medchemexpress LLC HY152093100MG

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YL-939 is a potent ferroptosis inhibitor. It inhibits ferroptosis by targeting the PHB2/ferritin/iron axis.

  • Efficiently protects cells from ferroptosis with varying IC50 values across different cell lines.
  • Reduces the level of reactive oxygen species in cytosolic and membrane lipids.
  • Improves ferritin protein expression and blocks autophagosomes/lysosomes, inhibiting ferritinophagy.
  • Ameliorates liver damage in an acetaminophen-induced acute liver injury model.
  • Inhibits cell death and inflammatory infiltration in liver tissues.

Catalog No. 50-003-73731


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