Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000221983

Medchemexpress LLC YM-244769 dihydrochloride | 1780390-65-9 | MFCD28160863 | >98.0% | 516.39 g/mol | C26H24Cl2FN3O3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1361825MG

Encompass_Preferred

YM-244769 dihydrochloride is a potent, selective, and orally active inhibitor of the Na+/Ca2+ exchanger (NCX) used in research to probe NCX-mediated calcium transport and for neuroprotection studies. It inhibits NCX-dependent 45Ca2+ uptake in NCX1, NCX2, and NCX3 transfectants in a dose-dependent manner.

  • IC50: 18 nM (NCX3), 68 nM (NCX1), 96 nM (NCX2).
  • Preferential inhibition of NCX3 relative to NCX1 and NCX2.
  • Orally active NCX inhibitor suitable for cellular and in vivo studies.
  • Demonstrated protection against hypoxia/reoxygenation-induced neuronal damage in models.
  • Storage: store sealed at 4°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
  • Molecular formula C26H24Cl2FN3O3; molecular weight 516.39 g/mol.

Catalog No. 50-002-21983


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.