Medchemexpress LLC Ym-53601 | 182959-33-7 | 99.4% | 372.86 g/mol | C21H22ClFN2O | 5 MG

Supplier:  Medchemexpress LLC HY100313A5MG

YM-53601 is a potent squalene synthase (FDFT1) inhibitor with demonstrated in vivo lipid-lowering activity. It reduces plasma cholesterol and triglyceride levels and inhibits squalene synthase derived from human hepatoma cells (reported IC50 79 nM), making it useful as a biochemical tool to probe sterol biosynthesis and related pathways.

• Potent squalene synthase inhibitor with reported IC50 of 79 nM.
• Demonstrated to reduce plasma cholesterol and triglyceride levels in vivo.
• Inhibits farnesyl-diphosphate farnesyltransferase 1 enzyme activity.
• Solid, white to light brown, supplied in small research quantities.
• High purity (batch specific), typically reported ~99.4%.
• Soluble in DMSO (100 mg/mL); store solid at 4°C and solutions at -20°C to -80°C.

Catalog No. 50-002-14356