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Abcam YM-58483 (CRAC Channel Inhibitor, BTP2), CRAC channel inhibitor, 1MG
Supplier: Abcam AB1444131MG
MW 421.3 Da, Purity >98%. Store-operated Ca²+ entry blocker. Potent, selective CRAC channel inhibitor. Inhibits thapsigargin-induced sustained Ca²+ influx (IC₅₀ = 100 nM). Suppresses cytokine production. Potent T-cell antiproliferative agent (IC₅₀ = 12.7 nM). Shows immunomodulatory and anti-inflammatory effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
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