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Cayman Chemical YM90KhydroCLOrID hydrate 10mg
SDP

Supplier:  Cayman Chemical 3068310 MG

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An AMPA receptor antagonist (Ki = 0.084 μM in a radioligand binding assay using rat brain membranes); selective for AMPA over kainate, NMDA-sensitive glutamate, and strychnine-insensitive glycine receptors (Kis = 2.2, >100, and 37 μM, respectively); intrastriatal administration inhibits AMPA-induced decreases in ChAT activity in rat striatum ex vivo; inhibits audiogenic seizures in susceptible DBA/2 mice with a minimum effective dose of 3 mg/kg, i.p.; intravenous infusion reduces infarct size in a rat model of focal cerebral ischemia induced by thrombotic MCAO in rats at 20 mg/kg per hour for 4 hours

Catalog No. 50-298-9424


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