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Apexbio Technology LLC Yohimbine Hydrochloride 65-19-0 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC N17045.1
Yohimbine Hydrochloride (65-19-0) is a small-molecule antagonist targeting -2 adrenergic receptors It is designed to selectively bind to pre- and postsynaptic -2 adrenergic receptors thereby reducing receptor-mediated inhibition and increasing the synaptic release of norepinephrine and dopamine Yohimbine Hydrochloride exerts its biological activity primarily through antagonism of -2 adrenergic receptors Reported IC50 values for inhibition at -2 adrenergic receptor subtypes generally range between 40 90 nM depending on receptor subtype and assay conditions Based on these pharmacological properties Yohimbine Hydrochloride holds research potential in neuroscience particularly in studies investigating the neurobiological mechanisms underlying anxiety depression and addiction-related behaviors
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