Thermo Scientific Chemicals Yohimbine hydrochloride, 99%

Description

Yohimbine hydrochloride, CAS # 65-19-0, is an α2-adrenergic receptor antagonist, which blocks the central α2-adrenegic receptors in the brain. | CAS: 65-19-0 | C21H27ClN2O3 | 390.91 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Yohimbine hydrochloride is an indole alkaloid derived from the tree bark
• It is an antagonist of α2-adrenergic receptors in the brain, reducing the effects of xylazine, which is an α2-adrenergic agonist

Applications

• Yohimbine hydrochloride blocks the central α2-adrenegic receptors in the brain
• It can reduce or eradicate effects of xylazine, which is an α2-adrenergic agonist
• It can have an antidiuretic effect

Specifications

Chemical Identifiers

• CAS: 65-19-0
• Molecular Formula: C21H27ClN2O3
• Molecular Weight (g/mol): 390.91
• MDL Number: MFCD00012674
• InChI Key: PIPZGJSEDRMUAW-VJDCAHTMSA-N
• Synonym: yohimbine hydrochloride, antagonil, yohimbe, yohimbine hcl, aphrodine hydrochloride, yohimbine monohydrochloride, unii-nb2e1yp49f, yohimbin hydrochloride usp, nb2e1yp49f
• PubChem CID: 6169
• IUPAC Name: methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride
• SMILES: [H+].[Cl-].COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@H]12

• Melting Point: 285°C to 288°C
• Color: White to Yellow
• Infrared Spectrum: Authentic
• Assay Percent Range: 99%
• Packaging: Glass bottle
• Quantity: 25 g
• Merck Index: 15, 10300
• Specific Rotation Condition: +99° (20°C c=1%,H₂O,dry substance)
• Specific Rotation: + 99
• Formula Weight: 390.9
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: Yohimbine hydrochloride

Safety and Handling

Hazard Category	GHS Signal Word: Danger
Hazard Statement	GHS H Statement: Toxic in contact with skin. May cause damage to organs through prolonged or repeated exposure. Toxic if inhaled.
Precautionary Statement	GHS P Statement: Wear protective gloves/protective clothing/eye protection/face protection. Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Gently wash with plenty of soap and water. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Do not breathe dust/fume/gas/mist/vapors/spray. WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
EINECSNumber	200-600-4

SDS

RUO – Research Use Only