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MilliporeSigma™ YUMM1.7 D4 Mouse Melanoma Cell Line

YUMM1.7D4 melanoma cell line is a diploid clone of YUMM1.7, developed as immunicompetent cell line

Supplier:  MilliporeSigma™ SCC227

Catalog No. SCC227MI


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Description

Description

  • Immunocompetent cell line that recapitulates genetic drivers found in a significant proportion of human melanomas
  • Diploid genotype of YUMM1.7D4 cells greatly enhances efficiency of CRISPR-based screens with higher frequency of biallelic knockout compared to tetraploid cells
  • Syngeneic with the immunocompetent C57/B1/6 mouse background, retaining genetic markers of the Braf/Pten mouse model in which melanoma tumors develop with short latency
Specifications

Specifications

Store in liquid nitrogen, Cells can be cultured 10 passages after initial thawing without significantly affecting cell marker expression and functionality
Cancer Cells
Cell Culture
≥ 1 x 106 Cells/Vial
SDS
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