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MilliporeSigma™ YUMM1.7 D5 Mouse Melanoma Cell Line SDS

YUMM1.7D5 mouse melanoma cell line is a diploid clone of YUMM1.7 cell line developed as an immunicompetent cell line

Supplier:  MilliporeSigma™ SCC228

Catalog No. SCC228MI


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Description

Description

  • Recapitulates genetic drivers found in a significant proportion of human melanomas
  • Originated from a 4-hydroxytamoxifen-induced melanoma tumor in a male C57/B1/6 mouse into which mutations from the Braf/Pten genetically-engineered mouse model had been introduced via backcrossing
  • Harbors Braf V600E mutation and is homozygous negative for wild-type Pten and Cdkn2
Specifications

Specifications

Store in liquid nitrogen, Cells can be cultured for 10 passages after thawing without significantly affecting cell marker expression and functionality
Cancer Cells
Cell Culture
≥ 1 x 106 Cells/Vial
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