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MilliporeSigma™ YUMMER1.7-H2B-GFP5 Mouse Melanoma Cell Line

Catalog No. SCC245MI Shop All MilliporeSigma Products
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1 x 10&sup6; Cells/Vial
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SCC245MI 1 x 10&sup6; Cells/Vial
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Description

YUMMER1.7-H2B-GFP5 mouse melanoma cell line for studies of immune checkpoint inhibition and mechanisms of antitumor responses

  • Both immunocompetent and reflective of the somatic mutations common in melanomas
  • YUMMER1.7 H2B-GFP carries three driver mutations of melanoma:
    • Braf V600E
    • Pten -/-
    • Cdkn2 -/- (1,2)
  • Harbors a high frequency of stable UV-induced somatic mutations which have shown to stimulate host adaptive immune response

Contains genetically modified organisms (GMO)

TRUSTED_SUSTAINABILITY

Specifications

Content And Storage Store in liquid nitrogen, Cells can be cultured for 10 passages after initial thawing without significantly affecting cell marker expression and functionality
Quantity 1 x 10&sup6; Cells/Vial
For Use With (Application) Cell Culture
Sample Type Cancer cells

For research purposes only

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