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Medchemexpress LLC (Z)-2-(4-((6-chloro-7-methyl-1H-indol-3-yl)methylene)-2,5-dioxoimidazolidin-1-yl)-2-(3,4-difluorophenyl) | 1416663-77-8 | >98.0% | 1 ML
Supplier: Medchemexpress LLC HY12008610MM 1ML
RO-5963 is a small-molecule research inhibitor that disrupts p53 binding to MDM2 and MDMX, activating the p53 pathway. Reported IC50 values are approximately 17 nM (p53-MDM2) and 24 nM (p53-MDMX). The compound is supplied as a 10 mM solution in DMSO (1 mL) or as solids in multiple mg quantities for research use.
- Dual inhibition of p53-MDM2 and p53-MDMX with low-nanomolar potency.
- Available as a ready-to-use 10 mM solution in DMSO for cell-based assays.
- Also available as solid packages for storage or custom formulation.
- Molecular formula C24H21ClF2N4O5; molecular weight 518.90 g/mol.
- Analytical purity typically ≥98% by HPLC where specified.
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