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Medchemexpress LLC (Z)-4EGI-1 | 901787-88-0 | 98.0% | 451.28 g/mol | C18H12Cl2N4O4S | 10 MG
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Supplier:  Medchemexpress LLC HY19831A10MG

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(Z)-4EGI-1 is the Z-isomer of the 4EGI-1 scaffold, a small-molecule inhibitor that disrupts the eIF4E-eIF4G protein-protein interaction and inhibits translation initiation. It binds eIF4E (Kd 8.74 μM) and shows an IC50 of 43.5 μM in reported assays, and has been used in cell-based studies of translation and anticancer activity. Provided as a research reagent for in vitro and cellular experiments.

  • Disrupts eIF4E-eIF4G interaction and inhibits translation initiation.
  • Measured binding to eIF4E (Kd 8.74 μM) and IC50 43.5 μM.
  • High purity (98.0%).
  • Molecular weight approximately 451.28 g/mol.
  • Suitable for in vitro and cell-based research applications.

Catalog No. 50-002-97205


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