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CPC Scientific Z-Asp-Glu-Val-Asp-AMC 0.5MG
Supplier: CPC Scientific CASP085A
AMC (7-amino-4-methylcoumarin) derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AMC peptides by caspases generates strongly fluorescent AMC that is monitored fluorimetrically at 440-460 nm with excitation of 340-350 nm. Caspase-3 and caspase-7 substratesSEQUENCE: Z-Asp-Glu-Val-Asp-AMCONE-LETTER SEQUENCE: Z-DEVD-AMCMOLECULAR FORMULA: C36H41N5O14MOLECULAR WEIGHT: 767.8STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: SYNONYMS: RESEARCH AREA: ApoptosisREFERENCES:Koeplinger KA, et al. (2000) Protein Expr Purif 18, 378-87Garcia-Calvo M, et al. (1998) J Biol Chem 273, 32608-13Thornberry NA, et al. (1997) J Biol Chem 272, 17907-11Rano TA, et al. (1997) Chem Biol 4, 149-55Margolin N, et al. (1997) J Biol Chem 272, 7223-8Mizushima N, et al. (1996) FEBS Lett 395, 267-71Faubion WA, et al. (1999) J Clin Invest 103, 137-45.SKU(s): CASP-085A, CASP-085B
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