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Medchemexpress LLC (Z)-FeCP-oxindole | 1137967-28-2 | 99.6% | 329.17 | 500 MG
Supplier: Medchemexpress LLC HY10844450MG
(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. It can significantly inhibit VEGFR1 and PDGFRα or β at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM.
- Target: VEGFR
- Pathway: Protein Tyrosine Kinase/RTK
- Storage: Powder: -20°C for 3 years, 4°C for 2 years; in solvent: -80°C for 6 months, -20°C for 1 month
- In vitro solubility: DMSO: 50 mg/mL (151.90 mM; need ultrasonic)
- IC50 & target: VEGFR2 (200 nM), VEGFR1
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