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Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 100 MG

Supplier: Medchemexpress LLC HY11006650MG
(Z)-Guggulsterone, a constituent of the Indian Ayurvedic medicinal plant *Commiphora mukul*, has been shown to inhibit the growth of human prostate cancer cells by inducing apoptosis. It also inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway. Additionally, (Z)-Guggulsterone acts as a potent FXR antagonist and has been observed to reduce ACE2 expression and SARS-CoV-2 infection.
- Inhibits growth of human prostate cancer cells by inducing apoptosis.
- Inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway.
- Acts as a potent FXR antagonist.
- Reduces ACE2 expression and SARS-CoV-2 infection.
- Decreases level of VEGF-R2 protein in HUVEC.
- Reduces ACE2 and SHP levels in primary airway and intestinal organoids.
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