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Medchemexpress LLC (Z)-Guggulsterone | 39025-23-5 | 99.4% | 312.45 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY11006650MG

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(Z)-Guggulsterone, a constituent of the Indian Ayurvedic medicinal plant *Commiphora mukul*, has been shown to inhibit the growth of human prostate cancer cells by inducing apoptosis. It also inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway. Additionally, (Z)-Guggulsterone acts as a potent FXR antagonist and has been observed to reduce ACE2 expression and SARS-CoV-2 infection.

  • Inhibits growth of human prostate cancer cells by inducing apoptosis.
  • Inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling pathway.
  • Acts as a potent FXR antagonist.
  • Reduces ACE2 expression and SARS-CoV-2 infection.
  • Decreases level of VEGF-R2 protein in HUVEC.
  • Reduces ACE2 and SHP levels in primary airway and intestinal organoids.

Catalog No. 50-003-43588


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