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Medchemexpress LLC Z-guggulsterone | 39025-23-5 | MFCD01310757 | 99.4% | 312.45 g/mol | C21H28O2 | 5 MG
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Supplier:  Medchemexpress LLC HY1100665MG

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(Z)-Guggulsterone is a plant-derived sterol (CAS 39025-23-5) isolated from Commiphora mukul. It acts as a farnesoid X receptor (FXR) antagonist with reported activities including induction of apoptosis, inhibition of angiogenesis, and modulation of ACE2 expression, and is used in biochemical and cell-signaling research.

  • Potent farnesoid X receptor (FXR) antagonist.
  • Induces apoptosis in multiple cancer cell lines.
  • Inhibits angiogenesis via the VEGF-VEGFR2-Akt pathway.
  • Reported to reduce ACE2 expression and SARS-CoV-2 infection in studies.
  • Suitable for biochemical and signaling pathway research applications.

Catalog No. 50-002-63438


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