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Medchemexpress LLC Z-VAD | 162852-62-2 | 99.8% | 437.44 | 50 MG
Supplier: Medchemexpress LLC HY16438850MG
Z-VAD is an irreversible, broad-spectrum pan-caspase inhibitor that can inhibit various caspases including caspase-3, -6, -7, -8, -9, with a weaker effect on caspase-2. It can block apoptosis signaling pathways, induce autophagy and necrosis in tumor cells, and exhibits anti-angiogenic activity. It is primarily used in research related to cancer radiosensitization and cell death pathway regulation.
- Irreversible, broad-spectrum pan-caspase inhibitor
- Inhibits caspases including caspase-3, -6, -7, -8, and -9
- Blocks apoptosis signaling pathways
- Induces autophagy and necrosis in tumor cells
- Exhibits anti-angiogenic activity
- Enhances sensitivity of breast and lung cancer cells to radiotherapy
- Prolongs growth delay of tumor xenograft models
- Well tolerated in studies
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