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AdipoGen Z-VAD-FMK (Cell permeable), 187389-52-2, MFCD02684037, 1 mg

Supplier: AdipoGen AGCP30002M001

MF: C22H30FN3O7, MW: 467.5, ≥95%, Appearance: White solid. Cell permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Potent inhibitor of caspase-1 activation in NLRP3/NALP3-induced cells. Used in apoptosis and inflammasome studies.
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