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AdipoGen Z-VAD-FMK Cell permeable
SDP

Supplier:  AdipoGen AGCP30002M005

Encompass_Preferred

Chemical. CAS 187389-52-2 and 634911-81-2. Formula C22H30FN3O7. MW 467.5. Synthetic. Cell permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Potent inhibitor of caspase-1 activation in NLRP3/NALP3-induced cells. Used in apoptosis and inflammasome studies.

Catalog No. 50-256-2463


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