Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000391710

Medchemexpress LLC Z-VAD(OMe)-FMK | 187389-52-2 | 98.2% | 467.49 | 50 MG
SDP

Catalog No. 5000391710
Encompass_Preferred

Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor. It is also an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor, irreversibly modifying UCHL1 by targeting its active site.

  • Cell-permeable and irreversible pan-caspase inhibitor.
  • Inhibits ubiquitin carboxy-terminal hydrolase L1 (UCHL1).
  • Suppresses caspase-3 activity in lung tissues and decreases the number of terminal dUTP nick-end labeling-positive cells (in vitro).
  • Reduces blood-brain barrier permeability, relieves vasospasm, abolishes brain edema, and improves neurological outcome in subarachnoid hemorrhage (in vitro).
  • Efficiently blocks cell death induced by SMN deficiency (in vitro).
  • Prolongs the survival rate of mice in models of lipopolysaccharide-induced acute lung injury (in vivo).

Catalog No. 50-003-91710 Supplier Medchemexpress LLC Supplier No. HY1665850MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor. It is also an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor, irreversibly modifying UCHL1 by targeting its active site.

  • Cell-permeable and irreversible pan-caspase inhibitor.
  • Inhibits ubiquitin carboxy-terminal hydrolase L1 (UCHL1).
  • Suppresses caspase-3 activity in lung tissues and decreases the number of terminal dUTP nick-end labeling-positive cells (in vitro).
  • Reduces blood-brain barrier permeability, relieves vasospasm, abolishes brain edema, and improves neurological outcome in subarachnoid hemorrhage (in vitro).
  • Efficiently blocks cell death induced by SMN deficiency (in vitro).
  • Prolongs the survival rate of mice in models of lipopolysaccharide-induced acute lung injury (in vivo).

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.