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Apexbio Technology LLC Z-WEHD-FMK(Synonyms: Z-WEHD fluoromethyl ketone, Z-WEHD-FMK inhibitor, Caspase-5 inhibitor Z-WEHD-FMK), 1mg, CAS: 210345-00-9.
Supplier: Apexbio Technology LLC A19241
Z-WEHD-FMK (CAS 210345-00-9) is a peptide-based inhibitor primarily targeting inflammatory caspases including caspase-1 -4 and -5 It irreversibly blocks caspase-mediated proteolytic cleavage interfering with cellular signaling pathways involved in inflammation and apoptosis Studies demonstrate that Z-WEHD-FMK treatment prevents Chlamydia-induced fragmentation of the Golgi apparatus by inhibiting golgin-84 cleavage thereby decreasing bacterial proliferation and altering lipid trafficking to pathogen-containing inclusions This inhibitor is frequently utilized in cell biology and infectious disease research to investigate caspase-related cellular processes and microbial pathogenesis mechanisms
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