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Medchemexpress LLC Z-WEHD-FMK | 210345-00-9 | 98.0% | 763.77 | 10 MG
Supplier: Medchemexpress LLC HYP011110MG
Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6 μM) and can be used to investigate cells for evidence of apoptosis.
- Potent, cell-permeable and irreversible caspase-1/5 inhibitor
- Exhibits robust inhibitory effect on cathepsin B activity
- Can be used to investigate cells for evidence of apoptosis
- Elicits near-complete blockage of C. trachomatis-induced cleavage of golgin-84
- Inhibits E. piscicida-induced ZF4 cells cytotoxicity and pyroptotic morphology
- Significantly induces a decrease in IL-1β release in bone marrow-derived macrophages
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