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Medchemexpress LLC Z-WEHD-FMK | 210345-00-9 | 98.0% | 763.77 | 5 MG
SDP

Catalog No. 5000425944
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Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also shows a robust inhibitory effect on cathepsin B activity (IC50=6 μM).

  • Blocks C. trachomatis-induced cleavage of golgin-84 and increases GM130 expression in cells.
  • Inhibits E. piscicida-induced ZF4 cell cytotoxicity and pyroptotic morphology.
  • Inhibits cytotoxicity induced by cytosolic LPS delivery.
  • Reduces IL-1β release in bone marrow-derived macrophages (BMDM) depending on metal ion concentration.

Catalog No. 50-004-25944 Supplier Medchemexpress LLC Supplier No. HYP01115MG
May include imposed supplier surcharges.
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Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also shows a robust inhibitory effect on cathepsin B activity (IC50=6 μM).

  • Blocks C. trachomatis-induced cleavage of golgin-84 and increases GM130 expression in cells.
  • Inhibits E. piscicida-induced ZF4 cell cytotoxicity and pyroptotic morphology.
  • Inhibits cytotoxicity induced by cytosolic LPS delivery.
  • Reduces IL-1β release in bone marrow-derived macrophages (BMDM) depending on metal ion concentration.

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