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Medchemexpress LLC Z-WEHD-FMK | 210345-00-9 | 98.0% | 763.77 | 5 MG

Supplier: Medchemexpress LLC HYP01115MG
Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also shows a robust inhibitory effect on cathepsin B activity (IC50=6 μM).
- Blocks C. trachomatis-induced cleavage of golgin-84 and increases GM130 expression in cells.
- Inhibits E. piscicida-induced ZF4 cell cytotoxicity and pyroptotic morphology.
- Inhibits cytotoxicity induced by cytosolic LPS delivery.
- Reduces IL-1β release in bone marrow-derived macrophages (BMDM) depending on metal ion concentration.
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