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Medchemexpress LLC (Z)-Zolucatetide ((Z)-FOG-001; I-67) | 98.2% | 2076.39 | 5 MG
Supplier: Medchemexpress LLC HYP10925A5MG
(Z)-Zolucatetide is a structural isomer of Zolucatetide and acts as a potent β-catenin inhibitor with an IC50 of <50 nM. It inhibits β-catenin and T-cell factor (TCF) transcription factor interaction, suppresses cell proliferation, and induces cell cycle arrest in target cells. It has shown anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts and can be used for the study of colon cancer.
- Potent β-catenin inhibitor with an IC50 of less than 50 nM.
- Inhibits β-catenin and T-cell factor (TCF) transcription factor interaction.
- Suppresses cell proliferation.
- Induces cell cycle arrest in target cells.
- Exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts.
- Useful for the study of colon cancer.
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