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Selleck Chemical LLC Z57346765 hydrochloride E8275-1G
SDP

Catalog No. 5000042980
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Z57346765 hydrochloride is an inhibitor of phosphoglycerate kinase 1 (PGK1) that binds to the ADP-binding pocket with a KD value of 2 09 10 M reducing PGK1 metabolic enzyme activity glucose consumption and lactate production It also inhibits DNA replication impairs DNA damage repair and induces cell cycle arrest in kidney renal clear cell carcinoma (KIRC) cells

Catalog No. 50-000-42980 Supplier Selleck Chemical LLC Supplier No. E82751G
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Z57346765 hydrochloride is an inhibitor of phosphoglycerate kinase 1 (PGK1) that binds to the ADP-binding pocket with a KD value of 2 09 10 M reducing PGK1 metabolic enzyme activity glucose consumption and lactate production It also inhibits DNA replication impairs DNA damage repair and induces cell cycle arrest in kidney renal clear cell carcinoma (KIRC) cells

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