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AdipoGen anti-Zinc-alpha-2-glycoprotein (human), mAb (Zagy-2) (100 µg)
Supplier: AdipoGen AG20B0066C100
Monoclonal Antibody. Recognizes human zinc-alpha-2-glycoprotein. Isotype: Mouse IgG1. Clone: Zagy-2. Applications: ELISA, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vivo experiments. Due to its expression in and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity.
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