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Apexbio Technology LLC Zalcitabine 7481-89-2 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B22235.1

Zalcitabine is a nucleoside analog inhibitor targeting viral reverse transcriptase a key enzyme promoting viral replication By competitively binding to the active site of reverse transcriptase zalcitabine terminates DNA chain elongation effectively inhibiting viral DNA synthesis In vitro studies have demonstrated inhibitory activity against HIV-1 with reported IC50 values ranging approximately from 0 03 to 0 3 M Zalcitabine is frequently utilized in biomedical research as an antiviral reference molecule for studying HIV therapeutic targets antiviral drug resistance and mechanisms of reverse transcription inhibition
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