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Medchemexpress LLC Zaprinast | 37762-06-4 | 99.88% | 50 MG

Supplier: Medchemexpress LLC HYB181650MG
Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5) that significantly increases cGMP levels in myocytes. It is also a G protein-coupled receptor 35 (GPR35) agonist, activating rat GPR35 strongly and human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.
- Selective inhibitor of cGMP-selective Phosphodiesterase (PDE5).
- Increases cGMP levels in myocytes.
- G protein-coupled receptor 35 (GPR35) agonist.
- Reduces vessel remodeling through antiproliferative and proapoptotic effects.
- Enhances spatial memory and diminishes exploratory activity in mice.
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