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Medchemexpress LLC Zaprinast | 37762-06-4 | 99.88% | 50 MG
SDP

Supplier:  Medchemexpress LLC HYB181650MG

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Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5) that significantly increases cGMP levels in myocytes. It is also a G protein-coupled receptor 35 (GPR35) agonist, activating rat GPR35 strongly and human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.

  • Selective inhibitor of cGMP-selective Phosphodiesterase (PDE5).
  • Increases cGMP levels in myocytes.
  • G protein-coupled receptor 35 (GPR35) agonist.
  • Reduces vessel remodeling through antiproliferative and proapoptotic effects.
  • Enhances spatial memory and diminishes exploratory activity in mice.

Catalog No. 50-004-12762


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