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Medchemexpress LLC Zardaverine | 101975-10-4 | C12H10F2N2O3 | 1 ML
Supplier: Medchemexpress LLC HY1548510MM/1ML
Zardaverine is an orally active and selective PDE3/4 inhibitor with potent bronchodilator activity. It selectively inhibits the proliferation of HCC cells, inducing apoptosis and cell cycle arrest (G0/G1 phase). Zardaverine demonstrates good antitumor potential and is effective in bronchial relaxation and reducing inflammation in asthma.
- Targets phosphodiesterase (PDE) and apoptosis
- Pathway: Metabolic enzyme/protease and apoptosis
- Storage for powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 2 years, -20°C for 1 year
- Soluble in DMSO (25 mg/mL)
- Soluble in 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline (≥ 2.08 mg/mL)
- Soluble in 10% DMSO, 90% corn oil (≥ 2.08 mg/mL)
- IC₅₀ target: PDE3, PDE4
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